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DTSTART:20220101T000000
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DTSTART;TZID=UTC:20230220T130000
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SUMMARY:Seminar - Diabetes No More: lessons from the DiRECT trial and beyond
DESCRIPTION:All are invited to the MRC Epidemiology Seminar: \nDiabetes No More: lessons from the DiRECT trial and beyond\nProfessor Mike Lean\, University of Glasgow\nThis hybrid seminar was held in the meeting rooms\, Level 4\, Wellcome-MRC Institute of Metabolic Science\, Addenbrooke’s Hospital\, Cambridge\, CB2 0QQ\, and online. \nWatch a recording of this seminar on YouTube. \nAbout this talk\nThree RCT trials\, conducted entirely in primary care using low-calorie formula diets for 8-12 weeks\, have reported remissions for 40-60% of participants including South Asians\, and 70-80% with weight loss >10kg\, well maintained at 2 years. Hypertension and NAFLD\, commonly accompanying T2D\, normalized for ~30%. Remission was accompanied by normalization of ectopic fat in liver and pancreas\, and insulin production capacity. With fewer serious adverse events\, total medical care costs fell and cost-effectiveness analysis projected people to live longer\, feel better and cost less. Remissions are strongly driven by weight loss\, but new methods are needed to support longer maintenance. \nAbout Professor Lean\n\nVisiting professor at University of Otago\, and University of Sydney.\nEstablished the first Department of Human Nutrition in a Scottish Medical School\, 1990- initially funded 10 years by Rank Prize Funds.\n ‘Broad-focus’ strategy: translational\, integrative\, research and teaching\, across all scientific disciplines within Human Nutrition.\nMain focusses are on obesity\, diabetes\, metabolic syndrome and health promotion.\nAwards include Diabetes UK-Rank Prize Lecture (2014)\, Banting Memorial Lecture (2020-21)\, Tenovus Medal for Research (2017)\nElected FRSE (National Academy of Scotland) (2018).\n\nExplore past seminars\nAll MRC Epidemiology Unit seminars and events where slides\, audio or video are available can be found at www.mrc-epid.cam.ac.uk/past-seminars/ \nSign up for future seminars\nTo sign up for future seminars and/or other alerts please visit www.mrc-epid.cam.ac.uk/subscribe/
URL:https://www.epi.ims.cam.ac.uk/event/seminar-diabetes-no-more/
LOCATION:Meeting rooms\, Level 4 Institute of Metabolic Science\, Addenbrooke’s Treatment Centre (ATC)\, Cambridge Biomedical Campus\, Cambridge\, CB2 0SL\, United Kingdom
CATEGORIES:MRC Epidemiology Unit Seminar
ORGANIZER;CN="MRC Epidemiology Unit":MAILTO:contact@mrc-epid.cam.ac.uk
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