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X-WR-CALDESC:Events for IMS Epidemiology
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DTSTART:20180101T000000
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DTSTART;TZID=UTC:20190215T133000
DTEND;TZID=UTC:20190215T143000
DTSTAMP:20190128T104735Z
CREATED:20190116T161916Z
LAST-MODIFIED:20190128T104735Z
UID:11381-1550237400-1550241000@www.epi.ims.cam.ac.uk
SUMMARY:Seminar - Longitudinal growth modeling: a tool for genetic discovery
DESCRIPTION:All are invited to the CEDAR/MRC Epidemiology Seminar by:\n \nDr Diana Cousminer\, Children’s Hospital of Philadelphia\, University of Philadelphia. \nLongitudinal growth modeling: a tool for genetic discovery \nSeminar room 2\, University of Cambridge School of Clinical Medicine\, CB2 0SP\n\n\nAbstract\n\nDistinct growth patterns during adolescence correlate with adverse health outcomes such as poor cardiometabolic health and risk for osteoporosis\, but the genetic mechanisms mediating differences in growth trajectories remain largely unknown. Longitudinal modeling using SuperImposition by Translation and Rotation (SITAR) breaks down complex growth trajectories into three components\, “size”\, “timing”\, and “velocity.” We utilize these parameters as phenotypes for input into genome-wide association studies (GWAS)\, to better understand the genetic determinants of increase in bone mineral density at distinct skeletal sites and height growth. \n\n\nAbout Dr Cousminer \n\nDr Diana Cousminer is a Postdoctoral Research Fellow at the Children’s Hospital of Philadelphia and the University of Pennsylvania. She received her PhD in Medical Genetics from the University of Helsinki and the Institute for Molecular Medicine Finland. Dr Cousminer’s work focuses on the genetics of early life traits\, in particular the timing of puberty and pubertal growth\, and how these traits are linked to later life health outcomes such as diabetes\, cardiometabolic health\, and osteoporosis. \n\n\nSign up for future seminars\nTo sign up for future seminars and/or other alerts please visit www.mrc-epid.cam.ac.uk/subscribe/
URL:https://www.epi.ims.cam.ac.uk/event/seminar-diana-cousminer/
LOCATION:Seminar room 2\, University of Cambridge School of Clinical Medicine\, CB2 0SP\, University of Cambridge School of Clinical Medicine\, Cambridge\, CB2 0SP\, United Kingdom
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